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Yoneda Labs

Chemistry at the speed of software.

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Yoneda Labs combines AI-assisted software with a high-throughput experimentation lab in San Francisco to address difficult chemistry problems. Its services cover reaction troubleshooting, reaction optimization, route scouting, library enablement and library synthesis. The lab uses automation, inert-atmosphere glovebox work, solid and liquid dispensing, and in-house LC-MS, NMR and prep-HPLC analysis and purification.

Its software products include Yoneda Predict, which proposes conditions for novel reactions using models trained on reactions run in its own HTE lab; Yoneda Optimize, which searches for process conditions; and Yoneda Analyze, which detects and integrates LC-MS peaks, associates them with masses and presents the data on a single page. The company also describes reactivity models and Bayesian optimization as part of its technology stack.

The offering is aimed at medicinal and process chemistry teams, with services and software positioned for reaction development, process development and library work. The pages describe demos and product access but do not state a free plan, trial, editions, seat-based or usage-based packaging.

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