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b12 labs

AI-powered chemical synthesis platform for planning complex routes, designing experiments,

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b12 labs is an AI-powered chemical synthesis platform that helps researchers design, optimize, and execute chemical reactions. It addresses the challenge of turning target molecules into practical, executable synthesis routes, covering the workflow from retrosynthesis planning through condition optimization to lab automation.

The platform comprises three main modules: Selenium, an agentic retrosynthesis system that generates ranked synthesis strategies with concrete steps and model confidence; Palladium, a condition-optimization tool that designs high-throughput-ready plate layouts screening catalysts, ligands, bases, and solvents; and Cobalt, which converts optimized conditions into automation-ready protocols for instruments such as Chemspeed and Opentrons. The tools are designed for natural-language interaction, requiring no coding, and can be used independently or together. The platform is SOC 2 Type 2 compliant.

Selenium, Palladium, and Cobalt are available as software tools through the platform's web application, allowing teams to adopt individual modules as needed. The platform is intended for pharmaceutical and biotech research teams working on complex, multi-step molecules, novel scaffolds, and compounds with challenging selectivity requirements.

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